The Smoler Proteomics Center, Headed by Prof. Arie Admon from the Department of Biology and managed by Dr. Tamar Ziv, the Center is the Israeli national infrastructure hub for proteome analysis. It was established by the Technion and Israel Ministry of Science to facilitate a direct access to state of the art technologies, instrumentation and knowhow in the fields of protein purification and analysis to researchers from universities, research institutes, hospitals, and biotechnology companies, from Israel and worldwide. Our staff includes six people with diverse background and skills (biology, chemistry, biomedical engineering and mass spectrometry).
Activities in the Center range from identifying and quantifying proteins to large-scale comparisons of proteins and their posttranslational modifications in healthy and diseased states. The Center offers direct access to the center’s technology and expertise, including protein and peptide mass spectrometry, micro-chromatography, two-dimensional chromatography, and electrophoresis as well as in analyzing minute amounts of proteins. The center activities are both services and research collaboration on a first comes, first served basis.
The in-house research focuses mainly on small cell lung carcinoma, ovarian carcinoma and leukemia, as well as autoimmune diseases. These types of projects include developing early diagnostic kits for cancer, development of cancer vaccines, identifying markers for autoimmune diseases, and examining changes in protein repertoires related to treatments.