Publications

 

PUBLICATIONS 

    1. Sheinboim D, Parikh S, Manich P, Markus I, Dahan S, Parikh R, Stubbs E, Cohen G, Zemser-Werner V, Bell RE, Ruiz SA, Percik R, Brenner R, Leibou S, Vaknine H, Arad G, Gerber Y, Keinan-Boker L, Shimony T, Bikovski L, Goldstein N, Constantini K, Labes S, Mordechai S, Doron H, Lonescu A, Ziv T, Nizri E, Choshen G, Eldar-Finkelman H, Tabach Y, Helman A, Ben-Eliyahu S, Erez N, Perlson E, Geiger T, Ben-Zvi D, Khaled M, Gepner Y, Levy C. An Exercise-Induced Metabolic Shield in Distant Organs Blocks Cancer Progression and Metastatic Dissemination. Cancer Res. 2022 Nov 15;82(22):4164-4178.
    2. Abu Hariri H, Braunstein I, Salti T, Glaser F, Gefen T, Geva-Zatorsky N, Ziv T, Benhar M. Global Thiol Proteome Analysis Provides Novel Insights into the Macrophage Inflammatory Response and Its Regulation by the Thioredoxin System. Antioxid Redox Signal. 2022 Oct 18.
    3. Mann G, Sulkshane P, Sadhu P, Ziv T, Glickman MH, Brik A. Antibody for Serine 65 Phosphorylated Ubiquitin Identifies PLK1-Mediated Phosphorylation of Mitotic Proteins and APC1. Molecules. 2022 Jul 29;27(15):4867.
    4. Parikh S, Parikh R, Michael K, Bikovski L, Barnabas G, Mardamshina M, Hemi R, Manich P, Goldstein N, Malcov-Brog H, Ben-Dov T, Glaich O, Liber D, Bornstein Y, Goltseker K, Ben-Bezalel R, Pavlovsky M, Golan T, Spitzer L, Matz H, Gonen P, Percik R, Leibou L, Perluk T, Ast G, Frand J, Brenner R, Ziv T, Khaled M, Ben-Eliyahu S, Barak S, Karnieli-Miller O, Levin E, Gepner Y, Weiss R, Pfluger P, Weller A, Levy C. Food-seeking behavior is triggered by skin ultraviolet exposure in males. Nat Metab. 2022 Jul;4(7):883-900.
    5. Abou Karam P, Rosenhek-Goldian I, Ziv T, Ben Ami Pilo H, Azuri I, Rivkin A, Kiper E, Rotkopf R, Cohen SR, Torrecilhas AC, Avinoam O, Rojas A, Morandi MI, Regev-Rudzki N. Malaria parasites release vesicle subpopulations with signatures of different destinations. EMBO Rep. 2022 Jul 5;23(7).
    6. Mukherjee S, Maddalena M, Lü Y, Martinez S, Nataraj NB, Noronha A, Sinha S, Teng K, Cohen-Kaplan V, Ziv T, Arandkar S, Hassin O, Chatterjee R, Pirona AC, Shreberk-Shaked M, Gershoni A, Aylon Y, Elazar Z, Yarden Y, Schramek D, Oren M. Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins. Proc Natl Acad Sci U S A. 2022 Apr 26;119(173).
    7. Goldhirsh G, Kravtsova-Ivantsiv Y, Satish G, Ziv T, Brik A, Ciechanover A. A short binding site in the KPC1 ubiquitin ligase mediates processing of NF-κB1 p105 to p50: A potential for a tumor-suppressive PROTAC. Proc Natl Acad Sci U S A. 2021 Dec 7;118(49).
    8. Korsensky L, Chorev D, Saleem H, Heller-Japheth R, Rabinovitz S, Haif S, Dahan N, Ziv T, Ron D. Regulation of stability and inhibitory activity of the tumor suppressor SEF through casein-kinase II-mediated phosphorylation. Cell Signal. 2021 Oct;86:110085.
    9. González-López MDC, Jijón-Moreno S, Dautt-Castro M, Ovando-Vázquez C, Ziv T, Horwitz BA, Casas-Flores S. Secretome Analysis of Arabidopsis-Trichoderma atroviride Interaction Unveils New Roles for the Plant Glutamate:Glyoxylate Aminotransferase GGAT1 in Plant Growth Induced by the Fungus and Resistance against Botrytis cinerea. Int J Mol Sci. 2021 Jun 24;22(13):6804.
    10. Shaihov-Teper O, Ram E, Ballan N, Brzezinski RY, Naftali-Shani N, Masoud R, Ziv T, Lewis N, Schary Y, Levin-Kotler LP, Volvovitch D, Zuroff EM, Amunts S, Regev-Rudzki N, Sternik L, Raanani E, Gepstein L, Leor J. Extracellular Vesicles from Epicardial Fat Facilitate Atrial Fibrillation. Circulation. 2021 Jun 22;143(25):2475-2493. doi: 10.1161/CIRCULATIONAHA.120.052009.
    11. Dekel E, Yaffe D, Rosenhek-Goldian I, Ben-Nissan G, Ofir-Birin Y, Morandi MI, Ziv T, Sisquella X, Pimentel MA, Nebl T, Kapp E, Ohana Daniel Y, Karam PA, Alfandari D, Rotkopf R, Malihi S, Temin TB, Mullick D, Revach OY, Rudik A, Gov NS, Azuri I, Porat Z, Bergamaschi G, Sorkin R, Wuite GJL, Avinoam O, Carvalho TG, Cohen SR, Sharon M, Regev-Rudzki N. 20S proteasomes secreted by the malaria parasite promote its growth. Nat Commun. 2021 Feb 19;12(1):1172.
    12. Richard S, Gross L, Fischer J, Bendalak K, Ziv T, Urim S, Choder M. Numerous Post-translational Modifications of RNA Polymerase II Subunit Rpb4/7 Link Transcription to Post-transcriptional Mechanisms. Cell Rep. 2021 Jan 12;34(2):108578.
    13. Udasin RG, Gottfried Y, Fabre B, Bercovich B, Ziv T, Ciechanover A. The p105 NF-ĸB precursor is a pseudo substrate of the ubiquitin ligase FBXO7, and its binding to the ligase stabilizes it and results in stimulated cell proliferation. Biochem Biophys Res Commun. 2021 Jun 18;558:224-230.
    14. Sulkshane P, Duek I, Ram J, Thakur A, Reis N, Ziv T, Glickman MH. Inhibition of proteasome reveals basal mitochondrial ubiquitination. J Proteomics. 2020 Oct 30;229:103949.
    15. Hakim-Eshed V, Boulos A, Cohen-Rosenzweig C, Yu-Taeger L, Ziv T, Kwon YT, Riess O, Phuc Nguyen HH, Ziv NE, Ciechanover A. Site-specific ubiquitination of pathogenic huntingtin attenuates its deleterious effects. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18661-18669. doi: 10.1073/pnas.2007667117.
    16. Braunstein I, Engelman R, Yitzhaki O, Ziv T, Galardon E, Benhar M. Opposing effects of polysulfides and thioredoxin on apoptosis through caspase persulfidation. J Biol Chem. 2020 Mar 13;295(11):3590-3600.
    17. Raldúa D, Casado M, Prats E, Faria M, Puig-Castellví F, Pérez Y, Alfonso I, Hsu CY, Arick Ii MA, Garcia-Reyero N, Ziv T, Ben-Lulu S, Admon A, Piña B. Targeting redox metabolism: the perfect storm induced by acrylamide poisoning in the brain. Sci Rep. 2020 Jan 15;10(1):312.
    18. Faria M, Prats E, Gómez-Canela C, Hsu CY, Arick MA 2nd, Bedrossiantz J, Orozco M, Garcia-Reyero N, Ziv T, Ben-Lulu S, Admon A, Gómez-Oliván LM, Raldúa D. Therapeutic potential of N-acetylcysteine in acrylamide acute neurotoxicity in adult zebrafish. Sci Rep. 2019 Nov 1;9(1):16467 1038/s41598-019-53154-w.
    19. Fabre B, Livneh I, Ziv T, Ciechanover A. Identification of proteins regulated by the proteasome following induction of endoplasmic reticulum stress. Biochem Biophys Res Commun. 2019 Sep 17;517(2):188-192.
    20. Pina B, Ziv T, Faria M, Ben-Lulu S, Prats E, Arick MA, Gómez-Canela C, García-Reyero N, Admon A, Raldúa D. Multi-omic analysis of zebrafish models of acute organophosphorus poisoning with different severity. Toxicol Sci. 2019 Jun 19:kfz133.
    21. Kaisari S, Shomer P, Ziv T, Sitry-Shevah D, Miniowitz-Shemtov S, Teichner A, Hershko A. Role of Polo-like kinase 1 in the regulation of the action of p31 in the disassembly of mitotic checkpoint complexes. Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11725-11730.
    22. Fabre B, Livneh I, Ziv T, Ciechanover A. Modulation of the cell cycle regulating transcription factor E2F1 pathway by the proteasome following amino acid starvation. Biochem Biophys Res Commun. 2019 Jun 4;513(3):721-725.
    23. Nigam A, Ziv T, Oron-Gottesman A, Engelberg-Kulka H. Stress-Induced MazF-Mediated Proteins in Escherichia coli. mBio. 2019 Mar 26;10(2):e00340-19.
    24. Faria M, Ziv T, Gómez-Canela C, Ben-Lulu S, Prats E, Novoa-Luna KA, Admon A, Piña B, Tauler R, Gómez-Oliván LM, Raldúa D. Acrylamide acute neurotoxicity in adult zebrafish. Sci Rep. 2018 May 21;8(1):7918.
    25. Roth L, Srivastava S, Lindzen M, Sas-Chen A, Sheffer M, Lauriola M, Enuka Y, Noronha A, Mancini M, Lavi S, Tarcic G, Pines G, Nevo N, Heyman O, Ziv T, Rueda OM, Gnocchi D, Pikarsky E, Admon A, Caldas C, Yarden Y. SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors. Sci Signal. 2018 Jan 30;11(515).
    26. Qutob N, Masuho I, Alon M, Emmanuel R, Cohen I, Di Pizio A, Madore J, Elkahloun A, Ziv T, Levy R, Gartner JJ, Hill VK, Lin JC, Hevroni Y, Greenberg P, Brodezki A, Rosenberg SA, Kosloff M, Hayward NK, Admon A, Niv MY, Scolyer RA, Martemyanov KA, Samuels Y. RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells. Sci Rep. 2018 Jan 12;8(1):653.
    27. Prats E, Gómez-Canela C, Ben-Lulu S, Ziv T, Padrós F, Tornero D, Garcia-Reyero N, Tauler R, Admon A, Raldúa D. Modelling acrylamide acute neurotoxicity in zebrafish larvae. Sci Rep. 2017 Oct 24;7(1):13952.
    28. Ziv T, Chalifa-Caspi V, Denekamp N, Plaschkes I, Kierszniowska S, Blais I, Admon A, Lubzens E. Dormancy in Embryos: Insight from Hydrated Encysted Embryos of an Aquatic Invertebrate. Mol Cell Proteomics. 2017 Oct;16(10):1746-1769.
    29. Fridman S, Flores-Uribe J, Larom S, Alalouf O, Liran O, Yacoby I, Salama F, Bailleul B, Rappaport F, Ziv T, Sharon I, Cornejo-Castillo FM, Philosof A, Dupont CL, Sánchez P, Acinas SG, Rohwer FL, Lindell D, Béjà O. A myovirus encoding both photosystem I and II proteins enhances cyclic electron flow in infected Prochlorococcus cells. Nat Microbiol. 2017 Oct;2(10):1350-1357.
    30. Schmitz M, Ziv T, Admon A, Baekelandt S, Mandiki SNM, L’Hoir M, Kestemont P. Salinity stress, enhancing basal and induced immune responses in striped catfish Pangasianodon hypophthalmus (Sauvage). J Proteomics. 2017 Sep 7;167:12-24.
    31. Liscovitch-Brauer N, Alon S, Porath HT, Elstein B, Unger R, Ziv T, Admon A, Levanon EY, Rosenthal JJ, Eisenberg E. Trade-off between Transcriptome Plasticity and Genome Evolution in Cephalopods. Cell. 2017 Apr 6;169(2):191-202.
    32. Ben-Lulu S, Ziv T, Weisman-Shomer P, Benhar M. Nitrosothiol-Trapping-Based Proteomic Analysis of S-Nitrosylation in Human Lung Carcinoma Cells. PLoS One. 2017 Jan 12;12(1)
    33. Hakim V, Cohen LD, Zuchman R, Ziv T, Ziv NE. The effects of proteasomal inhibition on synaptic proteostasis. EMBO J. 2016 Oct 17;35(20):2238-2262.
    34. Cohen-Kaplan V, Livneh I, Avni N, Fabre B, Ziv T, Kwon YT, Ciechanover A. p62- and ubiquitin-dependent stress-induced autophagy of the mammalian 26S proteasome. Proc Natl Acad Sci U S A. 2016 Oct 17. pii: 201615455
    35. Talmi-Frank D, Altboum Z, Solomonov I, Udi Y, Jaitin DA, Klepfish M, David E, Zhuravlev A, Keren-Shaul H, Winter DR, Gat-Viks I, Mandelboim M, Ziv T, Amit I, Sagi I. Extracellular Matrix Proteolysis by MT1-MMP Contributes to Influenza-Related Tissue Damage and Mortality. Cell Host Microbe. 2016 Oct 12;20(4):458-470.
    36. Braten O, Livneh I, Ziv T, Admon A, Kehat I, Caspi LH, Gonen H, Bercovich B, Godzik A, Jahandideh S, Jaroszewski L, Sommer T, Kwon YT, Guharoy M, Tompa P, Ciechanover A. Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination. Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4639-47.
    37. Engelman R, Ziv T, Arnér ES, Benhar M. Inhibitory nitrosylation of mammalian thioredoxin reductase 1: Molecular characterization and evidence for its functional role in cellular nitroso-redox imbalance. Free Radic Biol Med. 2016 Aug;97:375-85.
    38. Levin L, Srour S, Gartner J, Kapitansky O, Qutob N, Dror S, Golan T, Dayan R, Brener R, Ziv T, Khaled M, Schueler-Furman O, Samuels Y, Levy C. Parkin Somatic Mutations Link Melanoma and Parkinson’s Disease. J Genet Genomics. 2016 Jun 20;43(6):369-79.
    39. Lehmann G, Ziv T, Braten O, Admon A, Udasin RG, Ciechanover A. Ubiquitination of specific mitochondrial matrix proteins. Biochem Biophys Res Commun. 2016 Jun 17;475(1):13-8.
    40. Schmitz M, Mandiki SN, Douxfils J, Ziv T, Admon A, Kestemont P. Synergic stress in striped catfish (Pangasianodon hypophthalmus, S.) exposed to chronic salinity and bacterial infection: Effects on kidney protein expression profile. J Proteomics. 2016 S1874-3919(16)30178-6.
    41. Levitan S, Sher N, Brekhman V, Ziv T, Lubzens E, Lotan T. The making of an embryo in a basal metazoan: Proteomic analysis in the sea anemone Nematostella vectensis. Proteomics. 2015 Dec;15(23-24):4096-104.
    42. Erdmann I, Marter K, Kobler O, Niehues S, Abele J, Müller A, Bussmann J, Storkebaum E, Ziv T, Thomas U, Dieterich DC. Cell-selective labelling of proteomes in Drosophila melanogaster. Nat Commun. 2015 Jul 3;6:7521.
    43. Kravtsova-Ivantsiv Y, Shomer I, Cohen-Kaplan V, Snijder B, Superti-Furga G, Gonen H, Sommer T, Ziv T, Admon A, Naroditsky I, Jbara M, Brik A, Pikarsky E, Kwon YT, Doweck I, Ciechanover A. KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth. Cell. 2015 Apr 9;161(2):333-47.
    44. Lamdan NL, Shalaby S, Ziv T, Kenerley CM, Horwitz BA. Secretome of Trichoderma interacting with maize roots: role in induced systemic resistance. Mol Cell Proteomics. 2015 Apr;14(4):1054-63.
    45. Piterman R, Braunstein I, Isakov E, Ziv T, Navon A, Cohen S, Stanhill A. VWA domain of S5a restricts the ability to bind ubiquitin and Ubl to the 26S proteasome. Mol Biol Cell. 2014 Dec 15;25(25):3988-98.
    46. Ben-Lulu S, Ziv T, Admon A, Weisman-Shomer P, Benhar M. A substrate trapping approach identifies proteins regulated by reversible S-nitrosylation. Mol Cell Proteomics. 2014 Oct;13(10):2573-83.
    47. Lotan T, Chalifa-Caspi V, Ziv T, Brekhman V, Markovich Gordon M, Admon A, Lubzens E, Evolutionary conservation of the mature oocyte proteome, EuPA Open Proteomics, 2014 June, 3:27-36.
    48. Berko D, Herkon O, Braunstein I, Isakov E, David Y, Ziv T, Navon A, Stanhill Inherent asymmetry in the 26S proteasome is defined by the ubiquitin receptor RPN13. J Biol Chem. 2014 Feb 28;289(9):5609-18.
    49. Eliahoo E, Litovco P, Ben Yosef R, Bendalak K, Ziv T, Manor H. Identification of proteins that form specific complexes with the highly conserved protein Translin in Schizosaccharomyces pombe. Biochim Biophys Acta. 2014 Apr;1844(4):767-77.
    50. Cohen LD, Zuchman R, Sorokina O, Müller A, Dieterich DC, Armstrong JD, Ziv T, Ziv NE. Metabolic turnover of synaptic proteins: kinetics, interdependencies and implications for synaptic maintenance. PLoS One. 2013 May 2;8(5):e63191.
    51. Engelman R, Weisman-Shomer P, Ziv T, Xu J, Arnér ES, Benhar M. Multilevel regulation of 2-Cys peroxiredoxin reaction cycle by S-nitrosylation. J Biol Chem. 2013 Apr 19;288(16):11312-24.
    52. Kaplan B, Golderman S, Yahalom G, Yeskaraev R, Ziv T, Aizenbud BM, Sela BA, Livneh A. Free light chain monomer-dimer patterns in the diagnosis of multiple sclerosis. J Immunol Methods. 2013 Apr 30;390(1-2):74-80.